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2010 Mercedes-Benz E350 engine problems

16 complaints (9% of all complaints for this car). Typical mileage when it fails: 49,900. 1 crash reported.

owner complaints
16
of this car's complaints
9%
typical mileage
49,900
crashes
1
recalls
0

Which part fails

  • Exhaust system
    1

At what mileage

Complaints by mileage at the time of the problem.

0k-25k
25k-50k
50k-75k
75k-100k
100k-125k
125k-150k
150k-175k
175k-200k
200k+

Mercedes-Benz E350 engine problems in other years

2006201020152025

Specific symptoms reported on the 2010 Mercedes-Benz E350 engine

Phrases found in the owners' own descriptions, so one complaint can mention several symptoms.

Check engine light 10

Related recalls

No recalls on record for this model year.

What 2010 Mercedes-Benz E350 owners say

Most recent owner complaints, unedited.

Filed Jul 24, 2025 · Engine · TN

fast acceleration then slow down goes into limp mode . happens when passing a car or taking off fast like entering into traffic . very dangerous. will be calling mercedes benz tomorrow. bought car used approximately 4 months ago. thanks

Filed Apr 14, 2025 · Engine, Fuel system · KY

Smell gasoline on driver side. Can’t fill tank up or the smell is unbearable. Gas consumption is high. Engine light is on , suspension make a lot of noise, and ticking on driver side.

Filed Apr 4, 2025 · Engine · TN

does the engine in this car have a correct balance shaft?

Filed Feb 24, 2025 · Electrical, Engine · 183,000 miles · FL

The contact owns a 2010 Mercedes-Benz E350. The contact stated while driving at an undisclosed speed, the low battery warning light illuminated. The vehicle was driven to a nearby parking lot. The contact parked the vehicle and opened the hood. The contact stated that upon inspecting the vehicle, the contact noticed pieces of the serpentine belt on the engine. The contact turned the vehicle off. The contact went to a nearby Auto Parts store and purchased a new serpentine belt. The contact replaced the serpentine belt, and the vehicle was driven to the residence. The contact stated that upon checking the data on the instrument panel, the contact became aware of several error messages. In addition, the contact stated that while driving at an undisclosed speed, the steering wheel failed to turn in the intended direction. The contact stated that the steering wheel had seized. The contact turned off the vehicle and the steering wheel functionality returned. The contact stated that the low coolant warning light illuminated; however, the coolant level was checked and was sufficient. Additionally, the contact stated that the drive assist warning light was illuminated on the instrument panel. The vehicle was taken to two independent mechanics regarding the drive assist warning light; however, the failure could not be duplicated. The vehicle was not diagnosed or repaired by an independent mechanic or the dealer. The manufacturer was made aware of the failure. The failure mileage was approximately 183,000.

Filed Nov 18, 2024 · Engine · OH

August 2024, while driving on a 4 lane highway at 65 mph, a warning appeared on gauge cluster saying that Electronic Stability Control and Traction Control inoperable. This caused the car to reduce power, requiring me to quickly pull over. The car continued running but I was limited on mph and gear selection (aka Limp Mode). I turned the car off, allowing the systems to reset. After driving approximately 1 miles, the same warnings appeared. Fortunately, I was within a mile from home at the time so I was able to "Limp" the car home. The next day, I checked the car again by driving in my neighborhood with the result. I had the car transported on roll back to Express Oil and Tire in Barboursville, WV as my "local" MB dealer is an hour away. They checked the car and the Engine Control Module was defective and needed replacement. The cost of the service including new MB parts and programming would be $2,495. I tried for 2 months to secure funding to fix the car to no avail. I had the car towed on roll back again but back to my house. The car has sat since then.

Filed Mar 7, 2024 · Engine, Fuel system · FL

Smell gasoline when tank get filled up. Engine light is on , suspension make a lot of noise , power steering pump also

Filed Feb 24, 2023 · Driver assistance, Engine · 127,000 miles · NH

The contact owns a 2010 Mercedes-Benz E350. The contact stated that the engine was misfiring and shifted LIMP Mode. The contact stated that the check engine warning light was intermittently illuminated. The vehicle was not diagnosed or repaired. A dealer was not contacted. Upon investigation, the contact associated the failure with the federal safety agency Campaign Number: 22V168000 (Exterior Lighting, Electrical Stability Control, Engine, and Engine Cooling) however, the VIN was not included. The manufacturer had been informed of the failure. The failure mileage was approximately 127,000.

Filed Jan 19, 2018 · Engine · 85,000 miles · FL

During cold engine starting, a knocking can be heard in the engine. The knocking lasts approximately eight rotations, and then stops.

Filed Dec 13, 2017 · Engine · 49,884 miles · VA

The vehicle has only 50k miles. I am the only owner and I purchased the vehicle in 2010 (new) with only 9 miles. I have completed all required services to date. In may I had the ab service complete and the check engine light was on. I was told it was likely due to the need of having the spark plugs change based on time not mileage. Now I am being told the outcome of the check engine light on is due to a misfire code for cylinder one, failed sds compression test. Cylinder one failed cylinder leak down test at 80%. Exhaust valve seats failing causing exhaust valves not to fully close. We are unable to repair the valve seat on cylinder head and it is necessary to replace passenger side cylinder head. Only camshafts and cam adjusters can be transferred. New head will come with new valves. There are repeated reports from other owners with this same issue-resulting in enormous repair cost. This is a defect and mercedes-benz need to consume the cost, especially since the vehicle has less than $50k miles.

Filed Sep 21, 2017 · Electrical, Engine · 49,000 miles · MA

My 2010 e350 check engine light comes on and off but mostly on for 5 days out of 1 week, 2 days off. Been doing this since I got it bought it in nov of 2015. I was told by other owners that this may cost up to $8/12gs to get it fix. Why there wasn't a recall for this? Please expand, anyone??????

Questions about the 2010 Mercedes-Benz E350 engine

Does the 2010 Mercedes-Benz E350 have engine problems?

Owners have filed 16 complaints about the engine of the 2010 Mercedes-Benz E350, 9% of all its complaints.

At what mileage do 2010 Mercedes-Benz E350 engine problems start?

The typical (median) mileage in owner complaints is 49,900 miles.

Was there a recall on the 2010 Mercedes-Benz E350 engine?

There is no recall for this problem on this model year.

What year does the Mercedes-Benz E350 have bad engine?

The Mercedes-Benz E350 model years with the most engine complaints are 2006 (72 complaints), 2007 (33 complaints) and 2012 (21 complaints).

Other 2010 Mercedes-Benz E350 problems

Airbags 68Fuel system 20Electrical 17Suspension 17Brakes 14Transmission 14Body 11Steering 8Driver assistance 5Lights 5Acceleration 4Seats 4Tires 3Wheels 3

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