Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. 2021070006, internal code 21P1590208) to replace out-of-spec ignition coils on 657 vehicles from model year 2021, including the E-Class. My VIN was not included in the recall campaign but my vehicle is experiencing these exact symptoms as referenced in the first sentence. My vehicle has 48,000 miles.
Mercedes-Benz E350 misfire problems
17 of the 2,222 owner complaints about the Mercedes-Benz E350 describe misfire or rough idle, most of them for the 2021 model year.
- owner complaints
- 17
- worst model year
- 2021
- typical mileage
- 127,000
Is there a fix? There are 2 recalls for this area of the car. See below
By model year
- 20221
- 20214
- 20161
- 20143
- 20131
- 20122
- 20102
- 20072
- 20061
Often reported together
Check engine light 10Won't shift 3Loss of power 3Stalling 2Jerking 1Fuel smell 1Fuel pump 1
Trouble codes mentioned
P0306 1P0300 1P0017 1P0016 1
What owners say
Issue with fuel injection for Benz E350 2014 2014 Mercedes-Benz E350 fuel injection issues often stem from faulty injectors causing misfires, often on Cylinder 5, or a recalled fuel feed line. Symptoms include rough idling, reduced gas mileage, stalling, and check engine lights (P0300-P0306 codes).
Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K miles and Mercedes refused to repair the issue as the engine part failure isn’t common.
Major issue found with engine cylinder head in various models with 2.0 Liter Turbo charged engines (Engine code M260 or M264). Cylinder heads have premature wear at valve seats, causing engine misfires and unsafe driving conditions. (Sudden loss of power, even on freeways.) Mercedes-Benz had improved cylinder head design to mitigate this issue, thus proving that they knew it was their product quality that is causing these unsafe issues. Mercedes-Benz even put out a service bulletin to address these defective cylinder heads. This publication can be found under XENTRY, Topic Number LI01.30-P-072328, Version 8, published 9/26/2023. My contact at Mercedes Dealer informed me that they are seeing a drastic increase in this problem affecting roughly over 25% of the models with these engines. They are beginning to fail at around the same time as the warranty expires. There are numerous stories on the internet concerning this issue, examples can be found in the following links: https://www.facebook.com/groups/mercedesbenzowners/posts/10162557430080937/ https://www.mercedesgleforum.com/threads/cylinder-head-replacement-11-500.4399/ We contacted Mercedes-Benz US Headquarters, they do not believe it is their problem and throws petty money around in attempt to strong-arm owners to shut us down. All we request was for Mercedes-Benz to own up to their quality issues and handle the repairs at their expense. Please help me among all the other owners that this is affecting. Thank you in advance for your assistance in this matter.
My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to TSB LI01.30-P-072328, which documents valve seat wear in M260 engines. This is a known defect acknowledged by Mercedes in technical bulletins, and other customers in the U.S. have received warranty extensions or goodwill coverage. I was denied coverage even though this is a manufacturer defect that can lead to misfire, power loss, and potential stalling, posing a safety risk on the road. Mercedes-Benz USA refuses to cover the repair (~$7,600+), even though it relates to a factory-documented problem. I’m requesting that the federal safety agency investigate this engine defect, as it may qualify for a safety recall or mandatory extended warranty coverage. INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)
Since May 2024, I had taken my car in for repairs at 3 different shops for same exact issue diagnosed as leak from air intake system. It has been repaired 7 times since it first occurred in May 2024, and unfortunately it is still not resolved. This is a potential danger to the driver because all of a sudden there will be loud noise from the engine, car will start misfiring and slow down the speed. The previous 3 attempts of repair were made at Mercedes Benz of West Covina. The car is non drivable at the moment.
The engine is misfiring and not powering correctly during driving. Car is failing to take off and today almost caused an accident due to the car would not pull off from the traffic light with oncoming traffic due to loss of power. Safety was at risk due to an accident was almost caused due to car not moving in on coming traffic Dealership is citing that is needs to have a cylinder replaced but will not tell me why it needs to be replaced, why this has happened or what could have been done pre maintenance to avoid this issue Check engine light came on Dealer has been contacted, and was told this is a common issue for this to happen to newer cars, but will not fix the issue and extended warranty will not cover due to this is a manufacturer issue
The contact owns a 2010 Mercedes-Benz E350. The contact stated that the engine was misfiring and shifted LIMP Mode. The contact stated that the check engine warning light was intermittently illuminated. The vehicle was not diagnosed or repaired. A dealer was not contacted. Upon investigation, the contact associated the failure with the federal safety agency Campaign Number: 22V168000 (Exterior Lighting, Electrical Stability Control, Engine, and Engine Cooling) however, the VIN was not included. The manufacturer had been informed of the failure. The failure mileage was approximately 127,000.
Car was being driven at secondary road speed (~40MPH). Engine suddenly began to spudder and misfire terribly. Came to a stop light engine was idled roughly. Accelerated from stop, when check engine light turned on. Car went into limp MODE at a very dangerous rail road crossing and left turn intersection. Without acceleration, family was in danger of being hit by train and incoming traffic. Took car to Mercedes mechanic. Faulty parts were the Camshaft Position Solenoid valve, ignition cool. Short circuit in one part caused blown ignition fuse and cascading mechanical problems and safety risks. Repair cost so far is $1,100. Concern is the placement of the faulty part. It is exposed to high heat in the motor compartment and poses a fire hazard as well as a personal injury hazard to the occupants and driver.
Camshaft sensor leaking oil into engine harness and ecu. Misfire
Related recalls
Engine and engine cooling: engine: gasoline: turbo/supercharger
- What is wrong
- Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2020 C300, E350, and GLC300 vehicles equipped with turbocharged 4-cylinder gasoline engines. The screws that retain the turbocharger oil feed and return lines may not have been properly tightened, possibly resulting in an oil leak.
- Risk
- An oil leak in the presence of an ignition source such as hot engine or exhaust components can increase the risk of a fire.
- Remedy
- MBUSA will notify owners, and dealers will inspect the turbocharger oil lines and tighten them as necessary, free of charge. The recall began August 17, 2020. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2020070017.
Recall number 20V364000 · Recall details
Engine and engine cooling: engine
- What is wrong
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2016 Mercedes Benz E350, E400, E400 4Matic, E63 4M S AMG, E350 4Matic, E63-4M S AMG, 2015 CLS400, CLS400 4Matic, CLS550, CLS63-4M "P" AMG, and CLS550 4Matic vehicles manufactured April 16, 2015, to April 22, 2015. The integral steel cable that secures the rubber seal to the bulkhead might have been damaged due to the supplier rework of the rubber seal. In the event the rubber seal is not properly secured around the engine compartment, it is possible for the rubber seal to temporarily stick to the hood when it is opened and then may fall into the engine bay when the hood is closed.
- Risk
- If the rubber seal falls into the engine compartment, it may contact parts of the engine or exhaust system, increasing the risk of a fire.
- Remedy
- MBUSA will notify owners, and dealers will replace the rubber seal, in the engine compartment, free of charge. The recall began on September 2, 2015. MBUSA's number is 2015080001. Owners may contact MBUSA customer service at 1‑201‑573‑5339.
Recall number 15V505000 · Recall details
Questions about the Mercedes-Benz E350 misfire
Which Mercedes-Benz E350 years have misfire or rough idle problems?
The model years with the most reports are 2021 (4 complaints), 2014 (3 complaints) and 2007 (2 complaints).
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