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2019 Mercedes-Benz E 450 4matic problems

The most common problem on the 2019 Mercedes-Benz E 450 4matic is transmission and drivetrain. It has 2.0 times the complaints of a typical E 450 4matic model year.

Typical year2.0x the typical complaints
Owner complaints
4
Recalls
1
Service bulletins
384 warranty
Worst area
Transmission

The worst 2019 Mercedes-Benz E 450 4matic problems

Ranked by number of owner complaints. Mileage and cost come from what owners wrote.

  • Transmission
    3
  • Driver assistance
    1
  • Electrical
    1

Problems by type

Tap a problem to see which part fails, at what mileage and in which other years.

  • Transmission
    3
  • Driver assistance
    1
  • Electrical
    1

Recalls 1

Power train: driveline: universal jointReported April 3, 2026 · 24,092 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018 E 400 4MATIC Sedan, E 400 4MATIC Wagon, E 400 4MATIC Cabriolet, E 400 4MATIC Coupe, 2018-2020 Maybach S 560 4MATIC, S 560 4MATIC Coupe, S 450 4MATIC, 2019-2020 E 450 4MATIC Sedan, E 450 4MATIC Wagon, E 450 4MATIC Coupe, and E 450 4MATIC Cabriolet vehicles. The drive shaft universal joint may break, resulting in a sudden loss of drive power.
Risk
A sudden loss of drive power increases the risk of a crash.
Remedy
Dealers will inspect and replace the drive shaft as necessary, free of charge. Interim letters, notifying owners of the safety risk, were mailed May 22, 2026. Additional letters will be sent once the remedy is available. Owners may contact MBUSA customer service at 1‑800‑367‑6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on beginning April 10, 2026.

Recall number 26V216000 · Recall details

See all 1 recalls for the 2019 Mercedes-Benz E 450 4matic

Technical service bulletins for the 2019 Mercedes-Benz E 450 4matic 38

Bulletins tell dealers how to fix known problems. A warranty extension means the manufacturer pays for that repair for longer.

See all 38 bulletins for the 2019 Mercedes-Benz E 450 4matic

What 2019 Mercedes-Benz E 450 4matic owners say

Most recent owner complaints, unedited.

Filed Sep 28, 2026 · Transmission · 17,500 miles · FL

The contact owns a 2019 Mercedes-Benz E-450 4MATIC. The contact stated that while driving 35 MPH, the brake pedal was depressed, and the vehicle vibrated abnormally. The dealer was contacted by phone and made aware of the failure. The vehicle was taken to the dealer where the brakes and throttle body were repaired. The vehicle was repaired; however, the failure reoccurred. The vehicle was taken back to the dealer where it was confirmed that the failure was associated with an unrepaired recall. The contact received notification of the federal safety agency Campaign Number: 26V216000 (Power Train); however, the part was unavailable for the recall repair. The manufacturer was contacted by phone and a case was filed. The failure mileage was approximately 17,500.

Filed Aug 31, 2026 · Transmission · MA

My vehicle is subject to the federal safety agency Recall 26V216 involving the drive shaft universal joint. In March 2025, before the recall was announced, Mercedes-Benz of Carlsbad diagnosed my vehicle with a front driveline/drive shaft problem. I later paid $2,575 to have the drive shaft replaced using genuine Mercedes-Benz parts. Mercedes-Benz later sent me a recall notice stating that customers who already paid to correct the recall condition may be eligible for reimbursement. On May 27, 2026, I started the reimbursement process through Mercedes-Benz of Carlsbad. I submitted everything Mercedes requested, including the repair invoice, proof of payment, and documentation showing genuine Mercedes-Benz parts were used. When additional documentation was requested, I provided it. I was told I had submitted all required documents. However, Mercedes-Benz will not enter my claim into the reimbursement review process because the recall campaign is not yet “open” and the remedy is not yet available. Mercedes-Benz Star Support told the dealer: “Reimbursement can be claimed after campaign is in open status.” I escalated the issue with Mercedes-Benz USA and received the same answer. My concern is that this prevents the 60-day review process from even starting. 49 C.F.R. §573.13(g)(1) states: “The manufacturer shall act upon a claim for reimbursement within 60 days of its receipt.” If a claim is incomplete, §573.13 also requires the manufacturer to identify the missing documentation within 60 days. I was told I submitted everything required. I am not asking the federal safety agency to determine whether I am entitled to reimbursement or the amount. I am asking the federal safety agency to review whether Mercedes-Benz can accept all required claim documents but refuse to process the claim until the campaign becomes “open,” effectively postponing the 60-day process indefinitely. I do not need a future recall repair. I already paid to have my drive shaft replaced. My concern is that Mercedes-Benz has all the requested reimbursement

Filed Aug 2, 2026 · Driver assistance, Electrical · NJ

Vehicle was exhibiting erratic indications in all safety systems. Was checked out by dealer told all was OK. Two weeks later vehicle indicated warnings in various safety system, instrument cluster went dark, speedometer and tach were inop, blinkers did not work. Car taken to dealer again where it was determined that water incursion into passenger side foot well as the result of clogged sunroof drains had resulted in water damage to the signal acquisition module and other modules regulating the CAN Bus which were mounted in a location susceptible to water incursion and damage. Routine service does not include assuring that sunroof drains are open. Given the nature of computer systems in this vehicle such water damage has the potential of serious safety issues. These modules must be relocated to an area not prone to flooding. MBNA was contacted and provided no customer support whatsoever. The repair was almost $2500.

Filed Jun 25, 2026 · Transmission · NY

The contact owns a 2019 Mercedes-Benz E-450 4MATIC. The contact received notification of the federal safety agency Campaign Number: 26V216000 (Power Train). The local dealer was contacted and confirmed that parts were not yet available. The vehicle was not diagnosed or repaired. The manufacturer was contacted and referred the contact to the dealer for assistance. The contact had not experienced a failure.

Compare the 2019 Mercedes-Benz E 450 4matic

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Questions about the 2019 Mercedes-Benz E 450 4matic

Is the 2019 Mercedes-Benz E 450 4matic reliable?

Owners have filed 4 complaints about the 2019 Mercedes-Benz E 450 4matic, 2.0 times a typical E 450 4matic model year.

What is the most common problem with the 2019 Mercedes-Benz E 450 4matic?

Transmission and drivetrain, with 3 complaints. Next is driver assistance (1).

How many recalls does the 2019 Mercedes-Benz E 450 4matic have?

1 recall, covering power train.

Was there a recall on the 2019 Mercedes-Benz E 450 4matic transmission?

Yes, 1 recall: 26V216000. Check your VIN to see if your car still needs the free repair.

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