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2021 Mercedes-Benz S 500 problems

The most common problem on the 2021 Mercedes-Benz S 500 is engine and cooling. Its complaint count is close to a typical S 500 model year.

Typical yearClose to a typical year
Owner complaints
1
Recalls
7
Service bulletins
3013 warranty
Worst area
Engine

The worst 2021 Mercedes-Benz S 500 problems

Ranked by number of owner complaints. Mileage and cost come from what owners wrote.

  • Engine
    1

Problems by type

Tap a problem to see which part fails, at what mileage and in which other years.

  • Engine
    1

Recalls 7

Service brakes, hydraulic: foundation componentsReported February 24, 2025 · 20,339 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Risk
A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.
Remedy
Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2025030007.

Recall number 25V116000 · Recall details

Communication: auto crash notificationReported October 25, 2024 · 21 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S 580 4MATIC, S 500 4MATIC, and S 580 4MATIC vehicles. The emergency call system may fail to place an automatic or manual call and may not provide the vehicle location as intended.
Risk
A disabled emergency call system that prevents a vehicle occupant from contacting emergency services or fails to identify the vehicle location, can delay emergency responders and increase the risk of injury.
Remedy
Dealers will update the communication module software, free of charge. Owner notification letters were mailed December 6, 2024. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2024110002.

Recall number 24V807000 · Recall details

Back over prevention: display functionReported July 11, 2022 · 8,530 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 AMG EQS53, EQS580, EQS450, 2021 S500, S580, and Maybach S580 vehicles. The rearview camera may not display the rearview image due to a software error in the MBUX multimedia system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
Risk
An inoperative rearview camera display reduces the driver's rear view, increasing the risk of a crash.
Remedy
Dealers will update the MBUX multimedia system software, free of charge. Owner notification letters are expected to be mailed August 19, 2022. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2022080002.

Recall number 22V493000 · Recall details

Electrical system: softwareReported May 20, 2022 · 242,722 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
Risk
A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
Remedy
The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Recall number 22V365000 · Recall details

Steering: columnReported April 1, 2022 · 4 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic and S500 4Matic vehicles. The electrical connector to the steering column module may not be secured properly, which can disable gear shifts and/or safety features including the electronic stability program, the driver's air bag, and turn signal indicators.
Risk
Disabled safety features or the inability to shift gears can increase the risk of a crash or injury.
Remedy
Dealers will inspect and reinstall the cover for the electrical connector, as necessary, free of charge. Owner notification letters were mailed May 13, 2022. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2022040006.

Recall number 22V214000 · Recall details

Exterior lighting: turn signalReported March 18, 2022 · 9,156 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS 450, EQS 580, and 2021 S500 and S580 vehicles. A software error may disable the rear turn signals, hazard lights, and reverse lights.
Risk
Disabled rear turn signals, hazard lights, and reverse lights can reduce the vehicle's visibility to other driver's, increasing the risk of a crash.
Remedy
Dealers will update the rear signal software, free of charge. Owner notification letters were mailed May 2022. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2022040013.

Recall number 22V167000 · Recall details

Air bags: sensor: occupant classification: front passengerReported October 11, 2021 · 1,311 vehicles affected
What is wrong
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 S500, S580, and Maybach S580 vehicles. The air bag control unit software may deactivate the occupant recognition control unit, resulting in a deactivated front passenger air bag.
Risk
A deactivated passenger air bag increases the risk of injury during a crash.
Remedy
Dealers will update the air bag control unit software, free of charge. Owner notification letters were mailed December 1, 2021. MBUSA's number for this recall is 2021100010. Owners may contact MBUSA customer service at 1‑800‑367‑6372.

Recall number 21V789000 · Recall details

See all 7 recalls for the 2021 Mercedes-Benz S 500

Technical service bulletins for the 2021 Mercedes-Benz S 500 301

Bulletins tell dealers how to fix known problems. A warranty extension means the manufacturer pays for that repair for longer.

See all 301 bulletins for the 2021 Mercedes-Benz S 500

What 2021 Mercedes-Benz S 500 owners say

Most recent owner complaints, unedited.

Filed Dec 4, 2024 · Engine · 20,700 miles · FL

The contact owns a 2021 Mercedes-Benz. The contact stated while driving at 10 MPH, the vehicle stalls until the contact engages the vehicle in sport mode. The vehicle was not taken to an independent mechanic or dealer for diagnosis or repairs. The manufacturer was not notified of the failure and a case was opened. The contact was relating the failure to  the federal safety agency Campaign Number: 24V704000 (ENGINE AND ENGINE COOLING). The failure mileage was 20,700.

Compare the 2021 Mercedes-Benz S 500

Other model years

20212023

Questions about the 2021 Mercedes-Benz S 500

Is the 2021 Mercedes-Benz S 500 reliable?

Owners have filed 1 complaint about the 2021 Mercedes-Benz S 500, close to a typical S 500 model year.

What is the most common problem with the 2021 Mercedes-Benz S 500?

Engine and cooling, with 1 complaint.

How many recalls does the 2021 Mercedes-Benz S 500 have?

7 recalls, covering service brakes, hydraulic, communication and back over prevention.

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