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2016 Mercedes-Benz E350 problems

The most common problem on the 2016 Mercedes-Benz E350 is electrical system, typically around 41,166 miles. Its complaint count is close to a typical E350 model year.

Typical yearClose to a typical year
Year score
68/100
Owner complaints
51
Recalls
5
Service bulletins
1264 warranty
Worst area
Electrical
Fuel economy
23mpg

The worst 2016 Mercedes-Benz E350 problems

Ranked by number of owner complaints. Mileage and cost come from what owners wrote.

  • Electrical
    9
  • Body
    7
  • Visibility
    7
  • Airbags
    6
  • Acceleration
    5

Problems by type

Tap a problem to see which part fails, at what mileage and in which other years.

  • Electrical
    9
  • Body
    7
  • Visibility
    7
  • Airbags
    6
  • Acceleration
    5
  • Engine
    5
  • Steering
    5
  • Transmission
    5
  • Fuel system
    4
  • Brakes
    3
  • Driver assistance
    2
  • Lights
    2
  • Wheels
    2
  • Seat belts
    1
  • Seats
    1
  • Suspension
    1
  • Tires
    1

Recalls 5

CommunicationReported November 1, 2019 · 24,226 vehicles affected
What is wrong
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2013-2017 vehicles due to a software fault that may cause the date and time for the emergency call system (eCall) to differ from the actual date and time, potentially relaying an inaccurate vehicle location. For a full list of the affected models visit:
Risk
An inaccurate vehicle location may delay emergency responders, increasing the risk of injury.
Remedy
MBUSA has initiated an Over the Air (OTA) remote update. MBUSA will also notify owners, and dealers will check software for a successful OTA or update the communication module software as needed, free of charge. The recall began December 23, 2019. Owners may contact MBUSA customer service at 1‑800‑367‑6372. MBUSA's number for this recall is 2019120008.

Recall number 19V787000 · Recall details

Air bags: frontalReported October 6, 2017 · 495,290 vehicles affected
What is wrong
Mercedes-Benz USA, LLC. (MBUSA) is recalling these vehicles: 2014-2018 CLA250, CLA250 4Matic, CLA45 AMG 4Matic, 2015-2018 GLA250, GLA250 4Matic, GLA45 AMG 4Matic, C300 4Matic, C63S AMG, 2012-2014 C250, C350, C300 4Matic, E550 4Matic, 2013-2014 C63 AMG, 2012-2015 C250 Coupe, C350 Coupe, C63 AMG Coupe, 2013-2015 C350 4Matic Coupe, GLK250 4Matic BlueTec, GLK350, GLK350 4Matic, 2016-2017 C350e, C43 AMG, 2015 C400 4Matic, 2016-2018 C63 AMG, GLC300, GLC300 4Matic, 2017-2018 C300 Coupe, C300 4Matic Coupe, C43 AMG, C63 AMG Coupe, C63S AMG Coupe, C300 Cabriolet, C300 4Matic Cabriolet, C43 AMG Cabriolet, C63 AMG Cabriolet, C63S AMG Cabriolet, GLC300 4Matic Coupe, GLC43 AMG, GLC43 AMG Coupe, 2014 E350 Coupe, E350 4Matic Coupe, E350 Cabriolet, E400 Hybrid, 2015-2017 E400 Coupe, E400 4Matic Coupe, E400 Cabriolet, 2014-2017 E550 Coupe, E550 Cabriolet, B250e, 2014-2016 E250 BlueTec, E63 AMG 4Matic Wagon, 2012-2013 E350 BlueTec, 2012-2016 E350, E350 4Matic, 2015-2016 E400, E400 4Matic, 2012 E63 AMG, 2014-2015 E250 4Matic BlueTec, 2013-2016 E350 Wagon, 2017 GLC300d 4Matic, and 2018 GLC350e 4Matic. The driver's air bag may unexpectedly deploy due to insufficient grounding of the steering components if an electrostatic discharge occurs and the air bag clockspring is broken.
Risk
If the driver air bag inadvertently deploys, it can increase the risk of injury and a crash.
Remedy
MBUSA will notify owners, and dealers will add sufficient grounding to the steering components, free of charge. The recall began in December 6, 2017. Owners may contact MBUSA customer service at 1‑877‑496‑3691.

Recall number 17V627000 · Recall details

Electrical system: softwareReported March 14, 2017 · 51 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 AMG GT-S, GLC300, CLA250 and GLE300d 4Matic vehicles, 2013 C250, E350 BlueTec and G63 AMG vehicles, 2008-2014 C300 vehicles, 2013-2014 C300 4Matic and ML350 4Matic vehicles, 2009 C350 vehicles, 2014 CLS550, E350 4Matic, E350 Coupe 4Matic, E350 Wagon 4Matic, GLK350 and SL550 vehicles, 2012 CLS550 4Matic vehicles, 2012-2016 E350 vehicles, 2016-2017 GL450 4Matic vehicles, 2012-2014 ML350 4Matic BlueTec vehicles, 2015 S550, S550 4Matic and C300 4Matic Sedan vehicles, 2015-2016 C300 Sedan vehicles, and 2017 SL63 AMG vehicles. Various control units on these vehicles may have been updated with incorrect software, potentially affecting the correct deployment of the air bags in the event of a crash.
Risk
If the air bags do not deploy as intended in the event of a crash, there would be an increased risk of injury in the event of a crash.
Remedy
MBUSA will notify owners, and dealers will update software in the affected control units, free of charge. The recall began April 21, 2017. Owners may contact MBUSA customer service at 1‑800‑367‑6372.

Recall number 17V177000 · Recall details

Steering: electric power assist systemReported December 14, 2016 · 70 vehicles affected
What is wrong
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2013-2015 SL550, 2013-2014 SL63 AMG, 2014-2016 E350, 2014 E350 Cabriolet, E350 Coupe, 2014-2015 S550, 2015 E350 Bluetec, 2015-2016 E400, 2016 E550 Coupe, and Maybach S600 vehicles manufactured August 23, 2012, to August 14, 2015. The affected vehicles use an electric power steering system that may have improperly soldered contacts inside the control unit, potentially resulting in the power steering system deactivating while driving.
Risk
If the control unit pins lose connection, there would be a loss of electric power steering assist, increasing the risk of a crash. The increase in pin contact resistance can also increase the risk of a fire, even while the vehicle is parked and ignition is off.
Remedy
MBUSA will notify owners, and dealers will replace the electric power steering control unit, free of charge. The recall began October 13, 2017. Owners may contact MBUSA customer service at 1‑800‑367‑6372.

Recall number 16V899000 · Recall details

Engine and engine cooling: engineReported August 11, 2015 · 209 vehicles affected
What is wrong
Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2016 Mercedes Benz E350, E400, E400 4Matic, E63 4M S AMG, E350 4Matic, E63-4M S AMG, 2015 CLS400, CLS400 4Matic, CLS550, CLS63-4M "P" AMG, and CLS550 4Matic vehicles manufactured April 16, 2015, to April 22, 2015. The integral steel cable that secures the rubber seal to the bulkhead might have been damaged due to the supplier rework of the rubber seal. In the event the rubber seal is not properly secured around the engine compartment, it is possible for the rubber seal to temporarily stick to the hood when it is opened and then may fall into the engine bay when the hood is closed.
Risk
If the rubber seal falls into the engine compartment, it may contact parts of the engine or exhaust system, increasing the risk of a fire.
Remedy
MBUSA will notify owners, and dealers will replace the rubber seal, in the engine compartment, free of charge. The recall began on September 2, 2015. MBUSA's number is 2015080001. Owners may contact MBUSA customer service at 1‑201‑573‑5339.

Recall number 15V505000 · Recall details

See all 5 recalls for the 2016 Mercedes-Benz E350

Defect investigations

Desiccated Air Bag Inflator RuptureOpened September 17, 2021, still open

From 2000 through 2017, Takata produced millions of air bag inflators using two types of phase-stabilized ammonium nitrate ("PSAN") propellant -- propellant 2004 and propellant 2004L. After prolonged exposure to high temperature cycles and humidity, inflators using propellant 2004 can degrade, causing the propellant to burn too quickly when ignited. The rapid burning can cause the inflator to rupture during deployment, potentially causing serious or even fatal injury to vehicle occupants. See 2016 Blomquist Report at all frontal inflators using propellant 2004 that do not contain a "desiccant" (a substance that traps and holds moisture) in US vehicles are under recall. These "non-desiccated" inflators either have been or are required to be replaced.In some cases, the remedy part for these recalled inflators was, or will be, an inflator using either propellant 2004 or 2004L that does contain a desiccant. None of these "desiccated" remedy parts (which were installed in older model year vehicles) are currently under recall for a degradation concern. Certain subsets of desiccated PSAN inflators using propellant 2004 for use as original equipment, however, have been recalled for a degradation concern. All Takata inflators produced with propellant 2004L contain desiccant, and none of these desiccated inflators using propellant 2004L are under recall for a degradation concern. There have been no reported field ruptures in any non-recalled desiccated PSAN inflators.It is understood that desiccants fully saturate at some threshold, at which point any additional moisture will not be captured. This means the degradation process observed in non-desiccated inflators using propellant 2004 may also occur in non-recalled desiccated inflators using propellant 2004, assuming additional moisture enters the inflator and high temperature cycling occurs. Based on available information, desiccant saturation can occur within the first five years in the worst environments, and the time required for full saturation is affected by multiple factors. While no present safety risk has been identified, further work is needed to evaluate the future risk of non-recalled desiccated inflators using propellant 2004.Three entities -- Takata (now known as TK Global), the Independent Testing Coalition, and Exponent -- have been studying the long-term behavior of Takata desiccated PSAN inflators using propellant 2004L (as well as 2004) in the presence of moisture and temperature cycling. The research efforts, which include development of predictive modeling techniques and field sample analysis, are ongoing. To date, none of the researchers have identified field evidence showing that propellant 2004L is undergoing a degradation process that leads to aggressive deployment and potential rupture. However, the time in service of such inflators remains short compared to that of the inflators using propellant 2004. Further study is needed to assess the long-term safety of desiccated inflators using propellant 2004L.The Office of Defects Investigation is opening this investigation to examine whether a safety defect related to propellant degradation exists in non-recalled desiccated PSAN frontal inflators manufactured by Takata. This investigation will require extensive information on Takata production processes and surveys of inflators in the field. Lists of recall actions that may have used desiccated PSAN inflators as remedy parts, as well as the makes and models originally manufactured with them, is available with the downloadable version of this document (see -- note this information is subject to change/revision as the investigation proceeds). This investigation does not supersede EA15-001, which remains open.

EA21002

Technical service bulletins for the 2016 Mercedes-Benz E350 126

Bulletins tell dealers how to fix known problems. A warranty extension means the manufacturer pays for that repair for longer.

See all 126 bulletins for the 2016 Mercedes-Benz E350

2016 Mercedes-Benz E350 fuel economy

Official EPA estimates in miles per gallon (MPGe for electric). Ranges cover trims that share the same engine.

EngineDriveCityHighwayCombined
3.5L 6‑cylRWD2028-2923

What 2016 Mercedes-Benz E350 owners say

Most recent owner complaints, unedited.

Filed Jul 16, 2026 · Body, Suspension · VA

The rear subframe is defective and subject to premature corrosion and failure of parts that connect to the rear suspension. Due to the fracturing of the joints connecting to the suspension, my car was at risk of going out of control when needing to brake at higher speeds. The way the suspension component broke also risked damage to the gas tank if the car was driven over a large bump or pot hole. The problem was diagnosed by an independent repair service. The corrosion is not visible to an owner. It does not impact any body panels - only structural parts visible when the vehicle is on a lift. Mercedes Benz has provided an extended warranty for unlimited miles and 20 years to any owner of this model for a range of years and models. This was communicated to Mercedes Benz dealerships on March 10, 2023. However, since the vehicle is not subject to recall, I do not know how this was communicated to an owner. I did not receive anything alerting me to the problem. Mercedes Benz has my phone number on file.

Filed Mar 16, 2026 · Airbags, Seats · LA

Passenger seat capacity sensor fault. Will not activate passenger side air bag. Checked with obd scanner

Filed Jan 27, 2026 · Fuel system · NY

Fuel odor is very apparent (while idle) but difficult to identify location. Same models seem to have recalls for fuel injectors/rails but not this specific VIN. I believe the issue might be of similar recall. I will have the car diagnosed soon.

Filed Dec 5, 2025 · Body, Visibility · 140,000 miles · MS

The contact owns a 2016 Mercedes-Benz E350. The contact stated that water was leaking inside the vehicle through the seal around the windshield. The contact stated that upon manually pushing the windshield, the windshield was movable. Additionally, the contact stated that there was a windy sound coming through the windshield while driving. The vehicle was taken to Dunaway Glass Repair Company, where the windshield was being replaced. The vehicle was being repaired. The manufacturer was notified of the failure and informed the contact that the VIN was not under recall. The manufacturer referred the contact to the federal safety agency Hotline for the VIN to be added to a recall for potential reimbursement. The failure mileage was approximately 140,000.

Filed Oct 16, 2024 · Engine · CA

Since May 2024, I had taken my car in for repairs at 3 different shops for same exact issue diagnosed as leak from air intake system. It has been repaired 7 times since it first occurred in May 2024, and unfortunately it is still not resolved. This is a potential danger to the driver because all of a sudden there will be loud noise from the engine, car will start misfiring and slow down the speed. The previous 3 attempts of repair were made at Mercedes Benz of West Covina. The car is non drivable at the moment.

Filed Oct 11, 2024 · Driver assistance, Electrical · PR

Q1: Yes, it is available for inspection upon request. The instrument cluster showed some messages* randomly appearing/beeping on and off but there were other issues present: • Acceleration not possible in drive • At one point transmission would not shift from gear 3 • *Speedometer would go up and down randomly until it eventually stayed at 0 physically and digitally as I was going 55-60 MPH • *Check Engine light ON • *Red ‘Brake’ light ON • *ABS failed • *Distance sensors failed • *Stability control failed • *Electronic braking system failed • *Power steering failed • *Cruise control failed • *Mercedes PRE-SAFE failed • *Blind Spot Assist failed • *Lane Keeping Assist failed • *Adaptive Highbeam Assist failed • *Mileage was not displaying on the dash • Car would not shut off as I pushed the off button when I managed to eventually stop • *Climate temperature sensor reaching temps of 127 degrees Fahrenheit. Q2: I lost control of the vehicle while driving on the highway at relevant speeds. I was unable to safely stop for some time. If this had been at night, the issue would have been even more dangerous. This car has previously slammed on the brakes erroneously (no visually perceived danger of a forward collision). These previous brake slamming issues happened once in a traffic jam on the highway and once on a main road. Q3: Not that I know of or remember, no. Q4: Before this latest incident, I have previously left my car at the dealership’s workshop to be inspected for some relevant issues and concerns that I have had. It was there for almost 2 months on one occasion. Q5: There was only one warning lamp on the instrument cluster related to the collision prevention assist being inoperative. This message has been on the dash for maybe a year or more. The times it previously slammed on the brakes erroneously, no messages were on the dash.

Filed Jul 22, 2024 · Fuel system · FL

The fuel pump assembly Seals leaked fuel into my vehicle and saturated the interior of my car

Filed Jul 10, 2024 · Electrical · OH

I believe there is faulty wiring in the door speaker front passenger side. It causes crackling and humming. It lessens some when you turn ECO off. Concerned it could ignite a fire. Once told by dealer it’s caused by rain going into the door. Next time told that just to look at the problem would be around $600 because it has steel doors??

Filed Jun 4, 2024 · Body, Engine · VA

Dealership stated on 6/4/24 extensive rust and perforations on rear vehicle sub frame that can cause risk to driver of accident or injury. MBUSA is offering to replace sub frame part # 212 350 38 05. However dealership advised MBUSA is not offering to replace corroded brake lines or brake fluid exchange, and would need to come out of pocket. MBUSA failed to notify me of safety defect. Vehicle was purchased from MB of Arlington, VA in 4/2019 however dealership sold vehicle that is dangerous to drive. The vehicle also has additional safety defects such as a passenger tail light that does not work, and a license plate light not functioning. Dealership wants an additional $1500 to replace these (2) lights. Vehicle has low mileage at 60,000 and was purchased with 35,000 under MB CPO program. I am very disappointed in Mercedes Benz and have never had so many quality and safety issues with any of my prior E-Classes before. I contacted MBUSA and opened up a Executive Care Escalations Case [XXX}. There was no warning lights of the impending safety feature. The level of rust on the sub frame is horrifying, and this vehicle should never have been sold to me under MB CPO. In addition, the vehicle engine is leaking oil in multiple places and could catch fire in any moment. I have never seen so many issues on a vehicle with low mileage, especially with a Mercedes. Dealer is refusing to assist with cost, and wants 2K+ to replace engine gaskets. INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)

Filed May 6, 2024 · Visibility · VA

Recently (April 2024) we've noticed water drops forming on the inside of the vehicle along the top of the front windshield after a rain. Pushing outward along the top inside of the windshield glass indicates some movement of the glass. This applies all along the top inside of the windshield and not just one spot or area. So far, we have only observed water drops and have not observed any water pooling or puddling yet. We have not yet contacted a dealer; however we have conducted online research that strongly suggests that the windshield urethane adhesive seal is failing. Additional online information suggests that Mercedes had identified windshield urethane adhesive seal batch issues with certain 2016 E350 models. There have been no warning lamps or indicators from the vehicle. We have not observed any vehicle performance issues other than hearing a slight general whistling sound while driving at highway speeds above 55 mph, but that has been unchanged for years so it is likely not related to the windshield seal. The vehicle currently has approximately 30,000 miles on the odometer, and we are the second owners, having purchased it as a certified pre-owned vehicle with about 10,000 miles.

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Questions about the 2016 Mercedes-Benz E350

Is the 2016 Mercedes-Benz E350 reliable?

Owners have filed 51 complaints about the 2016 Mercedes-Benz E350, close to a typical E350 model year.

What is the 2016 Mercedes-Benz E350 year score?

The 2016 Mercedes-Benz E350 scores 68 out of 100 (average). The score compares it with the other model years of the Mercedes-Benz E350: 75 is a typical year, 50 means twice the usual complaints, and serious complaints and recalls lower it.

What is the most common problem with the 2016 Mercedes-Benz E350?

Electrical system, with 9 complaints, typically around 41,166 miles. Next is body (7).

How many recalls does the 2016 Mercedes-Benz E350 have?

5 recalls, covering communication, air bags and electrical system.

Was there a recall on the 2016 Mercedes-Benz E350 electrical?

Yes, 2 recalls: 19V787000, 17V177000. Check your VIN to see if your car still needs the free repair.

What year does the Mercedes-Benz E350 have the most electrical problems?

The Mercedes-Benz E350 model years with the most electrical complaints are 2014 (38 complaints), 2006 (19 complaints) and 2008 (19 complaints).

What gas mileage does the 2016 Mercedes-Benz E350 get?

Official estimates for the 2016 Mercedes-Benz E350 range from 23 mpg combined. The most efficient version (3.5L 6-cyl, RWD) gets 20 city and 28-29 highway.

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